Nsaale Body Detoxifier 500ML
NDA Reg. No. THA 1339
Bio-Syrup 100% Organic Free from alcohol, chloroform, narcotics and sedatives
Drug Description:
Nsaale Body Detoxifier
Bio-Syrup harnesses the potent herbal extract from Eucalyptus spp plant blends, renowned for its
cleansing properties. This all-natural formulation is meticulously crafted to
support and boost the body`s detoxification process, gently eliminating toxins,
excess oil, chemicals and impurities hence promoting overall holistic wellness leading
to body homeostasis. With its invigorating properties and time-tested botanical
benefits, Nsaale Body Detoxifier Bio-Syrup offers a refreshing approach to
revitalizing your body from within.
Active Organic Compounds:
Spirostan-6-ol amino, 9-Octadecenoic Acid, Arachidonic Acid, Alpha-D-glucose, Beta-D-Mannofuranoside, Methyl stearate, Tetradecanoic acid, N-Hexadecanoic acid, Dodecanoic acid, Glutaric acid, Dodecanoic acid methyl ester.
Indications:
Nsaale Body Detoxifier Bio-Syrup is basically used for cleansing
the body. This is done by helping the body to eliminate toxins, excess oil,
chemicals and impurities from the blood in the liver, where toxins are
processed for elimination. The body eliminates these excess toxins through the
skin, kidneys, intestines, lungs and lymphatic system during body
detoxification process. This helps in relieving symptoms of inflammation, pain,
blood clotting, infections, and brain function.
Warnings & Precautions:
Pregnancy & Lactation
Nsaale Body Detoxifier Bio-Syrup contains all-natural formulations which are generally recognized as safe (GRAS) when administered orally. No adverse side effects have been reported by pregnant and breastfeeding individuals though they should exercise caution and take the appropriate dosage as excessive consumption can lead to toxicity and mild side effects.
Side Effects:
Over dosing may cause some angina chest pain, mild diarrhea and anaphylaxis which stops once intake is stopped. Seek medical advice and take caution if you’re allergic to Eucalyptus spp or its components.
Drug Interactions:
No adverse effects have been reported regarding the simultaneous use of Nsaale Body Detoxifier Bio-Syrup along with other medications. Eucalyptus spp extract may interact with certain medications, such as anticoagulants (blood thinners) or medications metabolized by the liver. If you’re taking any medications or have underlying health conditions especially Large Kidney stones, Pancreatic stones, Bile duct stones and Bladder stones consult with your doctor as you may require immediate medical attention when those stones start to move in the organ to be excreted after reducing in their sizes.
Administration: Oral
Dosage:
Adults 20 ml & children below 12 years 5 to 10 ml before meals, twice a day or as prescribed by a physician.
Duration of Treatment:
Duration of treatment depends on the type and severity of the symptoms. Treatment should last within 2 to 10 weeks. Treatment should be maintained for 1-2 weeks after the symptoms have subsided. If symptoms persist seek medical advice.
Storage: Store below 30°C , Protect from heat and direct sunlight. Keep out of the reach of children.
Key Ingredients & Their Mechanisms of Action MoA:
- Spirostan-6-ol amino: Functions through a combination of mechanisms primarily inherited from its spirostan steroid backbone and modified by its amino and hydroxyl groups. Its primary actions involve disrupting microbial cell membranes, offering antimicrobial (especially antifungal and antibacterial) benefits by compromising pathogen integrity. It also possess anti-inflammatory properties by modulating cellular pathways and immune responses, thereby reducing skin irritation and redness. Furthermore, like some other steroidal compounds, it potentially support skin barrier function, contributing to improved moisturization.
- 9-Octadecenoic Acid (Oleic Acid): 9-Octadecenoic acid (Oleic Acid) exhibits antioxidant activity. It has potent hypolipidemic effects, significantly decreasing serum triglycerides (TG), total cholesterol (TC), LDL-C, and hepatic TG, potentially by reducing the activity of enzymes like acetyl coenzyme A (CoA) and acetyl transferase 2 (ACAT2) involved in cholesterol metabolism. It also possesses anti-inflammatory, anti-bacterial, and antifungal properties. The hypolipidemic action of 9-Octadecenoic Acid provides a direct and specific mechanism for the product's claim of "eliminating excess oil... from the blood." This establishes a clear cause-and-effect relationship between the compound's known pharmacology and the product's detoxifying indication related to lipids.
- Arachidonic Acid: Arachidonic acid (AA) is a key omega-6 polyunsaturated fatty acid that links nutrient metabolism to immunity and inflammation. It serves as a precursor for a wide array of highly bioactive metabolites, known as eicosanoids (e.g., prostaglandins, leukotrienes), which are central to triggering and mediating inflammatory responses. AA is released from cell membranes in response to cellular activation signals, including inflammation or infection. Increased levels of certain AA metabolites can lead to inflammatory damage. Arachidonic Acid is primarily known as a precursor to pro-inflammatory mediators. This suggests that the product is not simply reducing inflammation by removing AA, but rather modulating the body's natural inflammatory and immune responses, by influencing the balance of AA metabolites or supporting the resolution phase of inflammation.
- Alpha-D-glucose: Alpha-D-glucose plays a crucial indirect role in the body's detoxification processes primarily by supplying the energy (ATP and NADPH) required for the liver's intricate Phase I and Phase II detoxification enzymes. These enzymes, particularly the cytochrome P450s in Phase I and various conjugating enzymes in Phase II, are responsible for chemically transforming fat-soluble toxins and metabolic byproducts into more water-soluble forms that can then be safely excreted from the body via urine or bile. Additionally, glucose metabolism through pathways like the pentose phosphate pathway regenerates NADPH, a vital co-factor for the glutathione system and other antioxidant defenses, which are essential for neutralizing reactive oxygen species (ROS) often generated during detoxification and by environmental toxins. Thus, a sufficient and consistent supply of glucose is fundamental to supporting the energetic demands and enzymatic function of the body's natural detoxification machinery.
- Beta-D-Mannofuranoside: Beta-D-Mannofuranoside is a specific sugar molecule, a furanose (5-membered ring) form of mannose with a beta anomeric configuration. Unlike glucose, which is a primary energy source, beta-D-mannofuranoside itself is not directly a major energy metabolite in most organisms. Its mode of action is typically as a component of more complex glycans (carbohydrate chains), which play crucial roles in cellular recognition, signaling, and structural integrity. For instance, beta-D-mannopyranosides (the 6-membered ring form, but related) are essential components of N-glycans on proteins, plant beta-mannans, and various pathogen surface antigens. Therefore, beta-D-mannofuranoside, as a building block, participates in the complex enzymatic processes of glycosylation, where it is added to or cleaved from larger biomolecules by specific glycosyltransferases or glycosidases (like beta-mannosidases). This involvement allows it to contribute to the unique structures of glycoconjugates that are vital for host-pathogen interactions, immune responses, cell-cell communication, and maintaining overall biological function. Some derivatives are also used as enzyme substrates in biochemical assays to study the activity of glycosidases.
- Methyl stearate:. Its primary role is as an excipient, enhancing formulation and stability.
- Tetradecanoic acid: Tetradecanoic acid (myristic acid) does not directly neutralize or eliminate toxins in the body's detoxification processes. Instead, its mode of action is an indirect supportive role, primarily by being incorporated as a lipid anchor for specific proteins in cell membranes, including those in detoxifying organs like the liver. This N-myristoylation helps tether these proteins to membranes, where they often participate in crucial signaling and metabolic pathways. By contributing to healthy cell membrane structure and ensuring adequate cellular energy through its role in metabolism, tetradecanoic acid helps maintain the overall cellular integrity and function essential for the body's natural detoxification systems to operate effectively.
- N-Hexadecanoic acid: N-hexadecanoic acid (palmitic acid) is a common saturated fatty acid with antibacterial, anti-inflammatory, and antioxidant properties.
- Dodecanoic acid: Its primary therapeutic role in this product is antimicrobial.
- Glutaric acid: In the human body, glutaric acid's intended use is as a normal intermediate in the metabolic breakdown of specific amino acids, particularly lysine, hydroxylysine, and tryptophan. It's part of the intricate series of biochemical reactions that allow the body to extract energy from these protein building blocks and dispose of excess amino acids. Enzymes in the metabolic pathway ensure that glutaric acid is further processed into other compounds, preventing its accumulation and thus maintaining overall metabolic balance and cellular health.
- Dodecanoic acid methyl ester:. Its primary therapeutic role in this product is antimicrobial.