Nsaale Herbal Lotion 100 ml

Description:

Nsaale Herbal Lotion is specially formulated for supporting and restoring normal skin functions by providing soothing relief and nourishment for the skin. It boosts the excretory function of the skin by unclogging both the sweat and oil gland skin pores to offer a detoxifying effect to the skin, by helping the skin to excrete toxins, excess oil, chemicals and impurities through sweat leading to body homeostasis.  Crafted with the therapeutic properties of Eucalyptus spp, Curcuma longa (Turmeric) and Syzygium aromaticum (Clove), this lotion offers a trifecta of benefits. These natural herbal extracts are acknowledged by tradition as well as present-day science for their medicinal roles and properties including; antiseptic, antimicrobial, anti-inflammatory, antioxidant, antibacterial, natural analgesic, antinociceptive and antifungal. These herbal extracts effectively stop the growth of pathogens and calm inflamed areas, alleviate pain, soothe irritations while promoting skin healing as well as promote skin regeneration and complexion hence maintaining overall holistic health.  

Active Organic Compounds:

Squalene,  Phenanthrenequinone, (Z)-gamma-Atlantone, Dodecanoic acid,  Eicosane,  Ethyllinalool, Hexadecanoic acid methyl ester, Dodecanoic acid methyl ester, Octanoic acid methyl ester and Glycerin.

Indications:

Nsaale Herbal Lotion contains natural herbal extracts that are blended to strengthen and support healthy skin functions. It works synergistically as a soothe and helps in relieving Acne, Dark spots, Eczema, Tinea, Skin neoplasms, Dermatitis, Bleached skin, Inflammations, Bacterial and Fungal Skin Infections and used in chemoprevention or chemotherapy during Wounds and Burns healing to avoid scar tissue formation by preventing fibrosis of collagen fibers during the maturation and remodeling phase which leads to growth of normal parenchymal tissue again.   

Warnings & Precautions:

Pregnancy & Lactation

Nsaale Herbal Lotion contains natural herbs with high safety profile when applied topically. All herbs present in Nsaale Herbal Lotion have been recognized as safe for the skin.

Side Effects:

Nsaale Herbal Lotion is generally safe and well-tolerated. In few cases, it may have very mild irritable effect due to its healing power.

Drug Interactions:

No adverse effects have been reported regarding the simultaneous use of Nsaale Herbal Lotion along with other medications. It works effectively together with Nsaale Herbal Soap.

Dosage & Administration:

Apply topically on the affected parts and the whole body 2 times a day after bathing.

Ideal For: All ages.

Duration of Treatment:

Duration of treatment depends on the type and severity of the symptoms. Treatment should last within 4 to 24 weeks. Treatment should be maintained for 2-4 weeks after the symptoms have subsided. If symptoms persist seek medical advice.

Storage: Store below 30°C, Protect from heat and direct sunlight. Keep out of the reach of children.

Key Ingredients & Their Mechanisms of Action MoA:

• Eucalyptus spp: Eucalyptus oil, particularly its main component 1,8-cineole, is effective in reducing pain, swelling, and inflammation by modulating the immune response and inhibiting the production of pro-inflammatory cytokines like TNF-α, IL-1β, and IL-6. It also exhibits broad-spectrum antimicrobial activity, including antibacterial, antiviral (against HSV-1/2), and antifungal effects. Its analgesic and antinociceptive effects contribute to pain alleviation. The detailed mechanism of 1,8-cineole inhibiting pro-inflammatory cytokines provides a specific molecular basis for Eucalyptus's anti-inflammatory action, moving beyond a general statement to specific cellular and molecular processes, which is crucial for a pharmacology report.  
• Curcuma longa (Turmeric):. Its primary therapeutic roles in this product are anti-inflammatory, antimicrobial, and antioxidant.  
• Syzygium aromaticum (Clove): Clove contains bioactive compounds such as eugenol, α-humulene, and β-caryophyllene, which demonstrate potent antioxidant and anti-inflammatory properties by scavenging free radicals, modulating calcium channels, and suppressing pro-inflammatory pathways, including NF-κB. It also possesses significant antimicrobial (antibacterial, antifungal, antiviral) and anticarcinogenic activities. The combination of Eucalyptus, Turmeric, and Clove in this lotion exemplifies a synergistic botanical blend. Each botanical contributes distinct yet overlapping anti-inflammatory, antimicrobial, and antioxidant pathways , resulting in a more robust and comprehensive therapeutic effect across a wide spectrum of skin conditions. This multi-target approach is a common strategy in natural product medicine.  
• Squalene is a natural polyunsaturated hydrocarbon that is a major component of human sebum (10-16%). Its primary mechanism of action revolves around its role as a natural emollient and skin barrier component. Squalene integrates into the skin's lipid barrier, helping to reduce transepidermal water loss (TEWL) and maintain skin hydration. This action supports the skin's natural barrier function, protecting it from environmental aggressors and preventing dryness. It also acts as a natural antioxidant on the skin's surface, helping to neutralize free radicals generated by UV exposure and other environmental stressors, thus preventing oxidative damage to skin cells. Its inherent compatibility with skin lipids makes it highly effective for moisturizing and restoring skin suppleness without feeling heavy or greasy.
• Phenanthrenequinone:  Due to its mechanisms involving oxidative stress generation and disruption of cellular processes, some studies explore its use for antimicrobial effects against certain pathogens or in targeted therapies against skin cancer cells. In these specific, controlled contexts, its ability to induce cell damage might be leveraged to eliminate unwanted microbial growth or abnormal cell proliferation on the skin.
• (Z)-gamma-Atlantone is a sesquiterpene ketone found in essential oils, particularly from cedarwood. Its mechanism of action is largely attributed to its antimicrobial and anti-inflammatory properties. It is thought to exert its antimicrobial effects by disrupting the cell membranes of bacteria and fungi, leading to their growth inhibition or death. As an anti-inflammatory agent, it may modulate cellular pathways involved in the inflammatory response, helping to reduce redness and irritation in the skin. Additionally, like many terpenes, it can contribute a characteristic aroma to formulations.
  
• Dodecanoic acid (Lauric acid): Dodecanoic acid is a medium-chain saturated fatty acid with strong antimicrobial properties against bacteria, viruses (especially fat-enveloped), and yeasts. It inhibits bacterial growth by interfering with cell membranes and vital cellular processes, and by binding to enzymes like dihydrolipoamide acetyltransferase and fatty acid synthase. It can also have synergistic effects with other antibiotics. 
• Eicosane:  As an emollient and skin conditioning agent, eicosane forms a non-occlusive film on the skin's surface. This film helps to smooth the skin's texture and reduce rough patches, contributing to a soft and pliable feel. While it doesn't directly add moisture like a humectant (e.g., glycerin), it can help to reduce transepidermal water loss (TEWL) by creating a barrier that slows down the evaporation of water from the skin, thereby indirectly supporting skin hydration and comfort. Additionally, it can function as a solvent for other ingredients within the formulation, aiding in their dispersion and contributing to the overall feel and spreadability of the product.
• Ethyllinalool: The related compound Linalool acts on the inflammatory process and oxidative stress. It also possesses antibacterial and antifungal properties. These general properties  support the lotion's anti-inflammatory, antioxidant, and antimicrobial claims.   
• Hexadecanoic acid methyl ester: This compound has demonstrated significant antimicrobial effects against pathogenic bacteria and possesses antibacterial, anti-inflammatory, and antioxidant properties. It forms a light, non-greasy film on the skin, which helps to reduce moisture evaporation and improve the skin's softness and smoothness. 
• Dodecanoic acid methyl ester, or methyl laurate, is another fatty acid methyl ester derived from lauric acid. Its mechanism of action is primarily as an emollient and skin conditioning agent. Similar to other FAMEs, it helps to create a soft, smooth feel on the skin by forming a light film that reduces water loss. It also functions as a solvent for other lipophilic ingredients in the formulation, aiding in product consistency and spreadability. 
• Octanoic acid methyl ester, or methyl caprylate, is a shorter-chain fatty acid methyl ester. Its mode of action is as an emollient and skin conditioning agent, providing a light, non-greasy feel to the skin while helping to maintain hydration by reducing moisture evaporation. Due to its relatively smaller size, it can contribute to a lighter sensory feel compared to longer-chain esters. It also acts as a solvent and spreading agent in cosmetic formulations. 
• Glycerin is a potent humectant that works by attracting and drawing water from the environment into the skin's outermost layers (stratum corneum). This significantly increases the skin's water content, leading to enhanced hydration. Furthermore, glycerin helps to strengthen and restore the skin's natural barrier function, which is crucial for preventing water loss and protecting against external irritants. Its ability to improve skin hydration also contributes to a smoother and softer skin texture.